DNA/RNA Reverse Complement Calculator

Enter Sequence (DNA/RNA):

Result:

All calculations are performed locally in your browser. Your sequence data never leaves your device.

Features:

Supports both DNA and RNA sequences
IUPAC codes used for sequences (including ambiguous codes)
Cases (upper/lower) and all symbols (spaces, new lines, characters) are preserved
Secure: All computation done locally in your browser
Multiple FASTA sequences supported with header preservation